Exercise in early life has long-lasting benefits

Authors: Dharani M. Sontam, Mark H. Vickers, Elwyn C. Firth, Justin M. O'Sullivan

Source: ScienceDaily. ScienceDaily, 31 July 2017.
<www.sciencedaily.com/releases/2017/07/170731114710.htm>.

The researchers, from the Liggins Institute at the University of Auckland, found that bone retains a “memory” of exercise’s effects long after the exercise is ceased, and this bone memory continues to change the way the body metabolises a high-fat diet, and published these results in Frontiers in Physiology in a paper titled ‘A Memory of Early Life Physical Activity Is Retained in Bone Marrow of Male Rats Fed a High-Fat Diet’.

The research team compared the bone health and metabolism of rats across different diet and exercise conditions, zeroing in on messenger molecules that signal the activity of genes in bone marrow. Rats were either given a high-fat diet and a wheel for extra exercise in their cage, a high-fat diet but no wheel, or a regular diet and no wheel. In the rats given a high-fat diet and an exercise wheel, the early extra physical activity caused inflammation-linked genes to be turned down.

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