Routine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity

Authors: Bonet M, Ota E, Chibueze CE, Oladapo OT

Source: Cochrane Database of Systematic Reviews 2017, Issue 11. Art. No.: CD012137. DOI: 10.1002/14651858.CD012137.pub2.


Infectious morbidities contribute to considerable maternal and perinatal morbidity and mortality, including women at no apparent increased risk of infection. To reduce the incidence of infections, antibiotics are often administered to women after uncomplicated childbirth, particularly in settings where women are at higher risk of puerperal infectious morbidities.


To assess whether routine administration of prophylactic antibiotics to women after normal (uncomplicated) vaginal birth, compared with placebo or no antibiotic prophylaxis, reduces postpartum maternal infectious morbidities and improves outcomes.

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